Knoevenagel reaction mechanism pdf

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It is a knoevenagel reaction mechanism pdf of the aldol condensation. In this reaction the carbonyl group is an aldehyde or a ketone.


The catalyst is usually a weakly basic amine. Z for instance diethyl malonate, Meldrum’s acid, ethyl acetoacetate or malonic acid, or cyanoacetic acid. Z is an electron withdrawing functional group.