Please forward this error screen to 193. This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be robbins pathology notes pdf and removed.
Micrograph of a gastro-esophageal junction with pancreatic acinar metaplasia. The change from one type of cell to another may be part of a normal maturation process, or caused by some sort of abnormal stimulus. In simplistic terms, it is as if the original cells are not robust enough to withstand their environment, so they transform into another cell type better suited to their environment. If the stimulus causing metaplasia is removed or ceases, tissues return to their normal pattern of differentiation.
Metaplasia is not synonymous with dysplasia, and is not considered to be an actual cancer. It is also contrasted with heteroplasia, which is the spontaneous abnormal growth of cytologic and histologic elements.